smart freeze dryer technology

Pilot freeze drying systems Innovative technology

2021-9-3 · Pilot freeze dryers The new standard design of our popular pilot freeze dryers in the Epsilon 1-4 LSCplus, Epsilon 2-4 LSCplus, Epsilon 2-6D LSCplus and Epsilon 2-10D LSCplus series includes smart, innovative PAT tools for process optimization. The available packages provide optimal solutions for both product development and small-batch series

Freeze drying Technology - [PDF Document]

2015-7-21 · Freeze Drying New preservation technology TD 611 Also known as lyophilisation, lyophilization, or cryodesicion “lyophilization” – process for a product that…

[PDF] SMART TM FREEZE DRYER TECHNOLOGY : IMPACT …

Semantic Scholar extracted view of "SMART TM FREEZE DRYER TECHNOLOGY : IMPACT OF WATER RE-ADSORPTION OF POLYVINYLPYRROLIDONE ( PVP ) ON MANOMETRIC TEMPERATURE MEASUREMENTS ( MTM ) DURING PRIMARY DRYING" by H. Gieseler et al.

SMART Freeze Drying | iss

SMART Freeze Drying; LyoCapsule Freeze Dryer; Clinical and Production Freeze Dryers; Floor Model Manifold Freeze Dryers; General Purpose Freeze Dryer; Evaporators & Concentrators. Centrifugal Evaporators & Concentrators. HT- Evaporators; EZ-2 personal solvent evaporator; Rocket Series. Rocket Synergy evaporator; Rocket 4D Synergy evaporator

Freeze Dryer - Drug Discovery and Development

2009-10-26 · SMART freeze dryer technology is a patented system that puts the experience of the world’s top lyophilisation scientists into an easy-to-use cycle development tool. SMART freeze dryer technology enables development scientists to create a streamlined but safe process that can shave days off the production cycle.

Freeze Dryers – Biopharma Group – biopharma.uk

AutoMTM/SMART™ Freeze Dryer Technology – Primary drying cycle optimization tool for in depth product information; LyoFlux ® TDLAS Sensors – Accurate measurement of vapor mass flow for calculation of critical product attributes; Tempris ® Wireless Sensors – Real-time accurate and reliable product temperature measurement

Smart Freeze Drying - Martin Christ

2015-2-25 · Smart Freeze Drying Basic principles, optimum procedures and appliions. 4 . Contents 1 Introduction 4 2 Basic principles 6 3 Freeze Dryer Design 8 4 Procedures 10 4.1 Overview 10 4.2 Freezing 12 4.3 Primary drying and secondary drying 16 5 Practical aspects 24 5.1 Warm up

Virtis SMART Freeze Drying - United Scientific

2022-3-4 · SMART Freeze-Dryer Technology is a patented system that puts the experience of the world’s top lyophilization scientists into an easy-to-use cycle development tool. Developed exclusively with leading academics at The University of Connecticut and Purdue University, this technology is available on the LyoStar freeze-dryer (including a retrofit

SMART Freeze Drying | iss

SMART Freeze Drying; LyoCapsule Freeze Dryer; Clinical and Production Freeze Dryers; Floor Model Manifold Freeze Dryers; General Purpose Freeze Dryer; Evaporators & Concentrators. Centrifugal Evaporators & Concentrators. HT- Evaporators; EZ-2 personal solvent evaporator; Rocket Series. Rocket Synergy evaporator; Rocket 4D Synergy evaporator

Smart Freeze Dryer Technology : A Review | PharmaTutor

2020-9-12 · Smart Freeze Dryer Technology : A Review . About Authors Rajora Priyanka Singh*, Rathore Kamal Singh Faculty of Pharmacy, BN University, Udaipur-Raj.313001 *[email protected] ABSTRACT Lyophilization or freeze drying is a process in which water is remove from the product through the process of sublimation and desorption …

Smart Freeze Drying - Martin Christ

2015-2-25 · Smart Freeze Drying Basic principles, optimum procedures and appliions. 4 . Contents 1 Introduction 4 2 Basic principles 6 3 Freeze Dryer Design 8 4 Procedures 10 4.1 Overview 10 4.2 Freezing 12 4.3 Primary drying and secondary drying 16 5 Practical aspects 24 5.1 Warm up

New FTS SMART Freeze Dryer™ Technology from SP …

2010-5-27 · FTS SMART Freeze Dryer™ technology from SP Scientific, is a control software tool developed to enable development scientists to accelerate the task of developing and optimizing freeze drying cycles.

Optimisation of Primary Freeze-Drying Cycle Times

2012-12-10 · development freeze dryer, we ran a series of experiments where we controlled the nucleation temperature during the freezing phase and let the SMART technology automatically optimise the primary drying cycle. We then compared these results with a run where nucleation was uncontrolled and SMART optimised the primary drying cycle.

PAT for freeze drying: cycle optimisation in the

2007-1-25 · An example for process optimisation in the laboratory by MTM and SMART Freeze Dryer technology is shown in Figure 1 (page 63). A freeze drying cycle was performed for a 100 mg/mL sucrose sample solution (20 mL tubing …

FWIW the term "Smart Freeze Tehnology"

2021-10-31 · SMART Freeze-Dryer Technology is a PAT tool for identifying and reporting critical parameters during the product freeze-drying formulation process that can be later monitored during freeze-drying production to maintain product quality.

Use of manometric temperature measurement (MTM) and …

2007-12-1 · This report provides, for the first time, a summary of experiments using SMART™ Freeze Dryer technology during a 9 month testing period. A minimum ice sublimation area of about 300 cm 2 for the laboratory freeze dryer, with a chaer volume 107.5 L, was found consistent with data obtained during previous experiments with a smaller freeze dryer (52 L).

Freeze drying of orally disintegrating tablets containing

Orally disintegrating tablets (ODTs) were freeze dried in blisters using the Lyostar® II SMART™ Freeze Dryer Technology. ODT formulations either without non-water soluble particles (placebo) or containing large fractions (717 mg) of taste-masked naproxen sodium (NaS) granules were freeze dried. The …

SP Industries Release its Latest FTS Smart Freeze-Dryer

2007-11-8 · SP Industries Release its Latest FTS Smart Freeze-Dryer™ Technology. Noveer 8 2007 News SP Industries Release its Latest FTS Smart …

Optimisation of Primary Freeze-Drying Cycle Times

2012-12-10 · development freeze dryer, we ran a series of experiments where we controlled the nucleation temperature during the freezing phase and let the SMART technology automatically optimise the primary drying cycle. We then compared these results with a run where nucleation was uncontrolled and SMART optimised the primary drying cycle.

SMART LYO® Pharma Freeze Dryer - GEA engineering for …

SMART LYO® Pharma Freeze Dryers. Available in shelf sizes from 6.7 to 41.2 m² with a condenser capacity of up to 800 kg, SMART LYO® pharmaceutical freeze dryers are suitable for a wide range of appliions. The use of tried and tested GEA technology shortens both delivery and validation times, and enables customers to bring their products

Smart Freeze Drying - Martin Christ

2015-2-25 · Smart Freeze Drying Basic principles, optimum procedures and appliions. 4 . Contents 1 Introduction 4 2 Basic principles 6 3 Freeze Dryer Design 8 4 Procedures 10 4.1 Overview 10 4.2 Freezing 12 4.3 Primary drying and secondary drying 16 5 Practical aspects 24 5.1 Warm up

SMART Freeze Drying | iss

SMART Freeze Drying; LyoCapsule Freeze Dryer; Clinical and Production Freeze Dryers; Floor Model Manifold Freeze Dryers; General Purpose Freeze Dryer; Evaporators & Concentrators. Centrifugal Evaporators & Concentrators. HT- Evaporators; EZ-2 personal solvent evaporator; Rocket Series. Rocket Synergy evaporator; Rocket 4D Synergy evaporator

Freeze-drying process design by manometric temperature

Purpose: To develop a procedure based on manometric temperature measurement (MTM) and an expert system for good practices in freeze drying that will allow development of an optimized freeze-drying process during a single laboratory freeze-drying experiment. Methods: Freeze drying was performed with a FTS Dura-Stop/Dura-Top freeze dryer with the manometric …

Use of manometric temperature measurement (MTM) and …

Abstract This report provides, for the first time, a summary of experiments using SMART™ Freeze Dryer technology during a 9 month testing period. A minimum ice sublimation area of …

Freeze drying of orally disintegrating tablets containing

Orally disintegrating tablets (ODTs) were freeze dried in blisters using the Lyostar® II SMART™ Freeze Dryer Technology. ODT formulations either without non-water soluble particles (placebo) or containing large fractions (717 mg) of taste-masked naproxen sodium (NaS) granules were freeze dried. The …

"Smart" Freeze Drying Technology | Commercial Freeze …

SMART Freeze-Dryer Technology is a patented system that puts the experience of the world’s top lyophilization scientists into an easy-to-use cycle development tool. Developed exclusively with leading academics at The University of Connecticut and Purdue University, this technology is available on the LyoStar freeze-dryer (including a retrofit

SMART LYO® Pharma Freeze Dryer - GEA engineering for …

SMART LYO® Pharma Freeze Dryers. Available in shelf sizes from 6.7 to 41.2 m² with a condenser capacity of up to 800 kg, SMART LYO® pharmaceutical freeze dryers are suitable for a wide range of appliions. The use of tried and tested GEA technology shortens both delivery and validation times, and enables customers to bring their products

Smart Freeze Drying - Martin Christ

2015-2-25 · Smart Freeze Drying Basic principles, optimum procedures and appliions. 4 . Contents 1 Introduction 4 2 Basic principles 6 3 Freeze Dryer Design 8 4 Procedures 10 4.1 Overview 10 4.2 Freezing 12 4.3 Primary drying and secondary drying 16 5 Practical aspects 24 5.1 Warm up